Man-made THC improves headache in clinical trials

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Clues to the anti-headache mechanisms of cannabis can be found by looking at headache conditions that are relieved by reducing intracranial pressure. 

Dexanabinol, a synthetic cannabinoid, has been found to relieve intracranial pressure and improve outcomes after traumatic brain injury.

In addition, a double-blind, placebo-controlled trial of 26 patients found that a synthetic form of THC (Nabilone) was “significantly more effective” than Ibuprofen in reducing pain intensity.

It was also suggested that the anti-vomiting properties seen in the treatment of nausea brought on by chemotherapy might also be effective in treating migraine.

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