Both had a positive response to the treatment, with no evidence of disease progression for at least two years, and they are both alive.
CBD is being credited for improving the quality of life and possibly extending it for two patients diagnosed with a deadly form of brain cancer, according to research out of Brazil and published in Frontiers in Oncology, January 2019.
CBD capsules were added to the patients’ treatment regime, which included chemo-radiation.
The researchers said that one of the patients saw a “remarkable remission in altered areas of the diseased brain.”
And both had a positive response to the treatment, they said, with no evidence of disease progression for at least two years.
“This observation might highlight the potential effect of CBD to … improve chemo-radiation responses that impact survival,” the researchers said.
They said these outcomes are uncommon in patients who receive traditional treatments only.
No significant effect on liver or heart
The researchers found that CBD did not significantly affect liver or heart functions.
“Even with the prolonged use of CBD, the two patients did not develop any significant alterations in blood counts/plasma biochemistry.”
They had few symptoms of fatigue and nausea and were able to maintain their usual work and play sports during their treatment.
Both patients used vaporisers to inhale THC-rich cannabis flowers to reduce chemo-radiation side effects in their first year of treatment.
The research was led by:
Paula Baseggio Dall Stella and Marcos Vinicius Calfat Maldaun, both of Sirio Libanes Hospital, São Paulo, Brazil.
Case Report: Clinical Outcome and Image Response of Two Patients With Secondary High-Grade Glioma Treated With Chemoradiation, PCV, and Cannabidiol was published in Frontiers in Oncology and edited by Mark Ware, McGill University (on leave) Montreal, Canada.
Dr. Ware is Chief Medical Officer at Canopy Growth